Course 2025-2026 a.y.

21018 - CAUSAL INFERENCE

Department of Decision Sciences

Course taught in English
31
DAIHS (6 credits - II sem. - OBS  |  SECS-S/01)
Course Director:
ANTONIO LIJOI

Classes: 31 (II sem.)
Instructors:
Class 31: ANTONIO LIJOI


Suggested background knowledge

Solid knowledge of the contents of the Advanced Statistics for Health Sciences course. Familiarity with the topics in the Machine Learning course will also be helpful.

Mission & Content Summary

MISSION

While introductory statistics courses develop a multivariable thinking approach that relies on well-known association measures for studying dependence, in health and biomedical applications, one is more often interested in the causal effect of an intervention, or treatment, on an outcome. Lectures will provide both a methodological and a hands-on perspective on several problems, wherein the ultimate goal is to link data analysis to causal conclusions. The course will start with the simpler setting of randomized experiments, before addressing more complex situations where causal relationships are inferred from observational data. Practical examples based on public health applications will be developed throughout.

CONTENT SUMMARY

  • Review of measures of association. Contingency tables, risk difference, risk ratio, odds ratio, Simpson’s paradox.
  • Basic ideas of causal inference as a missing data problem. The potential outcomes framework. Counterfactuals and causal effects. Average treatment effects.
  • Randomized experiments: Fisher’s exact test and Neyman’s approach to repeated sampling.
  • Observational studies. Unconfoundedness and propensity scores.
  • Regression discontinuity designs.
  • Causal survival analysis.
  • Unmeasured confounding and instrumental variables methods.
  • Bayesian causal inference.
  • Applications in health.
     

Intended Learning Outcomes (ILO)

KNOWLEDGE AND UNDERSTANDING

At the end of the course student will be able to...
  • Provide an overview of the potential outcomes approach for causal inference.
  • Understand the basic assumptions underlying causal analysis.
  • Master statistical methods for learning causal relationships.

 

APPLYING KNOWLEDGE AND UNDERSTANDING

At the end of the course student will be able to...
  • Identify causal inference problems in health applications.
  • Analyze causal inference problems and identify the most suitable research design for addressing them, both with experimental and observational data.
  • Apply causal inference methods to real-world data, either experimental or observational, with the aid of software tools.

Teaching methods

  • Lectures

DETAILS

Face to face lectures on campus


Assessment methods

  Continuous assessment Partial exams General exam
  • Written individual exam (traditional/online)
    x

ATTENDING AND NOT ATTENDING STUDENTS

For determining the final assessment, students must choose between the following two options

 

1) The general exam, at the end of the course.

 

2) The combination of
2.1) A group project presentation or a group paper presentation, accounting for 40% of the final grade. Such presentations will take place during the course.
2.2) The general exam, accounting for 60% of the final grade, at the end of the course.

As for 2.1), each group is identified by the instructors and must express their preference over presenting a paper versus a project.

 

Project: a group will be assigned a dataset for which a causal analysis must be conducted using the tools that have been discussed during the course. The causal analysis and the results must be presented, with slides, and students must point out connections with the material presented during the course.

Paper: a group will be assigned a research paper on causality and will have to deliver a presentation discussing it, with slides. The presentation should summarize the main findings of the paper and emphasize the connections with the topics discussed during the course.

General exam: it consists of a written test, with questions on both the methodological and the applied parts of the course, and aims at testing students’ understanding of the statistical foundations and the practical uses of modern approaches to causal inference problems. 


Teaching materials


ATTENDING AND NOT ATTENDING STUDENTS

  • Ding, P. (2024). A first course in causal inference. CRC Press. A preliminary draft of the textbook is available at https://arxiv.org/pdf/2305.18793
  • Additional references will be provided during the course.
Last change 29/05/2025 09:14